Bam32
웹Monoclonal Antibody for studying DAPP1/BAM32 (Tyr139) phosphate. Cited in 2 publications. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously … 웹2012년 10월 26일 · In T cells, the adaptor Bam32 is coupled to Erk activation downstream of the TCR by an unknown mechanism. We characterized in Jurkat cells and primary T …
Bam32
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웹The levels of PI(3,4)P₂ and PI(3,4,5)P₃ have precise and profound effects on PKB and other molecules such as TAPP and Bam32. This study has contributed new insight into the PI 3-kinase signaling pathway from the aspect of phosphoinositide lipid function. 웹2012년 10월 26일 · Exogenous Bam32-YFP expression in Jurkat T cells increased Erk activation (Figures 1B and 1C), which correlated with changes in two of the core kinase components of the Erk cascade, Raf-1 (Figure 1B) and Mek-1 (Figure 1C).Raf-1 catalytic activity was elevated, and increased pRaf-1 on the activating S338 site was observed …
웹The B cell adaptor molecule of 32 kDa (Bam32) is an adaptor that links the B cell antigen receptor (BCR) to ERK and JNK activation and ultimately to mitogenesis. After BCR cross-linking, Bam32 is recruited to the plasma membrane and accumulates within F-actin-rich membrane ruffles. Bam32 contains one Src homology 2 and one pleckstrin homology … 웹2008년 4월 29일 · Bam32 (B lymphocyte adapter molecule of 32 kDa) is an adapter protein expressed in some hematopoietic cells including B and T lymphocytes. It was previously shown that Bam32-deficient mice have defects in various aspects of B cell activation including B cell receptor (BCR)-induced Erk activation, BCR-induced proliferation and T-independent …
Bam32 (B lymphocyte adapter molecule of 32 kDa), also known as DAPP1 and PHISH, is an SH2 and pleckstrin homology (PH) domain-containing adapter molecule expressed in B cells, T cells, dendritic cells and macrophages (1, 2). Bam32 is found at the cell membrane and has high affinity for lipid products in the … 더 보기 Intramural Research Program of the National Institutes of Health; National Cancer Institute; Center for Cancer Research. 더 보기 Bam32 expression has been detected in mouse thymic and splenic T cells, albeit at a lower (mRNA) level than in splenic B cells (2). Since Bam32 … 더 보기 Our studies reveal several defects of Bam32-deficient T cells. TCR-mediated spreading, a measure of cytoskeletal function, was impaired as was TCR-mediated cellular proliferation and elaboration of several … 더 보기 웹Scopri foto stock e immagini editoriali di attualità di K구리휴게텔⋇【Bam32.Com】안산풀싸롱⊫마포휴게텔⋗여주오피⊚용인노래방⊣ su Getty Images. Scegli tra immagini premium su K구리휴게텔⋇【Bam32.Com】안산풀싸롱⊫마포휴게텔⋗여주오피⊚용인노래방⊣ della migliore qualità.
웹Bam32, a B cell adaptor molecule 32 kD in size, was originally identified during screens for genes highly ex-pressed in human germinal center (GC) cells (4). Bam32 contains an NH2-terminal src homology 2 (SH2) domain, one potential tyrosine phosphorylation site, and a COOH-terminal pleckstrin homology (PH) domain but no appar-
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