Dead helicase
WebApr 15, 2024 · DEAD-box RNA helicases: The driving forces behind RNA metabolism at the crossroad of viral replication and antiviral innate immunity. DEAD-box RNA helicases, … WebDEAD-box RNA helicases, which also comprise a large family, are also involved in a range of RNA processing events. Since their discovery as nucleic acid unwinding enzymes, …
Dead helicase
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WebSep 30, 2010 · DEAD-box RNA helicases play various, often critical, roles in all processes where RNAs are involved. Members of this family of proteins are linked to human disease, including cancer and viral infections. DEAD-box proteins contain two conserved domains that both contribute to RNA and ATP binding. WebFeb 15, 2006 · RNA helicases of the DEAD-box protein family have been shown to participate in every aspect of RNA metabolism. They are present in most organisms where they work as RNA helicases or RNPases.
WebMay 16, 2024 · Asp-Glu-Ala-Asp (DEAD)-box RNA helicase 3 (DDX3), an ATP-dependent RNA helicase, is associated with RNA splicing, mRNA export, transcription, translation, and RNA decay. Recent studies revealed that DDX3 participates in innate immune response during virus infection by interacting with TBK1 and regulating the production of IFN-β. In … WebFeb 13, 2009 · SHPRH contains 2 partial SNF2 domains and 1 each of PHD finger, RING finger, linker histone, and DEAD helicase domains. SHPRH also has a nuclear localization signal. The mouse and human proteins share about 86% amino acid identity, and homologous sequences were found in several lower animal species and plant. Northern …
WebDEAD box proteins are considered to be RNA helicases and many have been found to be required in cellular processes such as RNA … WebMar 5, 2024 · The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response. EMBO J. 27, 2135–2146 (2008). [PMC free article] [Google Scholar] 9. Gu L., Fullam A., Brennan R., Schröder M., Human DEAD box helicase 3 couples IκB kinase ε to interferon regulatory factor 3 activation. Mol. Cell. ...
WebDNA helicase: an enzyme that catalyzes the energy-dependent unwinding of the DNA double helix during DNA replication.
WebAug 4, 2015 · Here we show that an RNA helicase, helicase 1 (HEL-1), extends the lifespan of the roundworm Caenorhabditis elegansby up-regulating the longevity transcription factor forkhead box O (FOXO). Our finding suggests that an RNA helicase can have rather specific roles in animal longevity. ptbs online therapieWebMay 30, 2006 · DEAD-box ATP-dependent RNA helicase 42 Gene RH42 Status UniProtKB reviewed (Swiss-Prot) Organism Arabidopsis thaliana (Mouse-ear cress) Amino acids 1166 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Align Download Add a publication Entry … hotard hallWebOct 19, 2024 · Four DEAD-box RNA helicase genes ( lmo0866, lmo1246, lmo1450, lmo1722) have been identified in L. monocytogenes EGD-e [ 14, 15, 16 ]. However, the precise mechanisms mediated the impact of the different RNA helicases of L. monocytogenes in capacity to grow at low temperature, motility, and other phenotypes … ptbs rehaWebFeb 26, 2024 · Other helicases, such as RNA helicase aquarius (AQR) and the DEAD Box helicase also resolve R-loops [1,5,9,17,20,21]. Similarly, topoisomerase I resolves supercoils, which prevents the formation of transcription-induced R-loops. These have been extensively reviewed elsewhere [8,16,22,23]. ptbs phasenWebOct 1, 2024 · Several DEAD-box RNA helicases have been reported to provide drought tolerance (Table 1). Pea DNA helicase 45 (PDH45) is a dual helicase with DNA and RNA unfolding activity [ 9 ]. Its overexpression in sugarcane stabilizes the cell membrane and activates DREB2-induced stress-responsive genes to provide drought stress tolerance [ … hotard general contractingWebFeb 1, 2024 · Cruciat et al. (2013) identified the DEAD box RNA helicase DDX3 as a regulator of the Wnt (see 164820)-beta-catenin (116806)M network, where it acts as a regulatory subunit of CK1-epsilon (600863): in a Wnt-dependent manner, DDX3 binds CK1-epsilon and directly stimulates its kinase activity, and promotes phosphorylation of the … ptbs sorckWebSep 19, 2024 · C-terminal helicase domain of the DEAD-like helicases. This hierarchy of DEAD-like helicases is composed of two superfamilies, SF1 and SF2, that share almost … hotard hall texas a\\u0026m