Ift88 function

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August undefined, 2024

Web15 jun. 2012 · Ift具有双向转运功能，其一定要拥有一套特殊的装置，包括ift运动蛋白（kinesin-II和dynein），Ift转运单位（IFT particle subunits），以及被转运的分子（cargo … Web22 sep. 2024 · More specifically, IFT88 is required at minus end of kinetochore-bound-microtubules to recruit the microtubule binding protein NuMA (Nuclear mitotic apparatus …

Intraflagellar Protein 88 Interactome Analysis: A Bioinformatics ...

WebIFT88 (intraflagellar transport protein 88; also known as TG737 or TTC10) is a component of IFT particles and required for cilium biogenesis. Defects in IFT88/Tg737 lead to … Web14 aug. 2013 · Intraflagellar transport (IFT) is required for the assembly and maintenance of cilia, as well as the proper function of ciliary motility and signaling. IFT is powered by … psychologist cumming ga

BBS4 - an overview ScienceDirect Topics

Web15 dec. 2024 · Cilia are involved in a plethora of motility and sensory-related functions. Ciliary defects cause several ciliopathies, some of which with late-onset, suggesting cilia … Web29 jul. 2010 · Surprisingly, initial analysis in zebrafish suggested that cilia might not be involved in Hh signal transduction in this important model species, as ift57, ift88 and ift172 mutant embryos, in which intraflagellar transport is disrupted, do not exhibit overt loss-or gain-of-function Hh phenotypes. Web15 feb. 2007 · This suggests that IFT88/polaris has others functions in higher eukaryotic organisms. In agreement with this idea, recent studies have demonstrated that … psychologist crystal river fl

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Web15 feb. 2024 · Gene Snapshot Gene Group Also Known As IFT88, osm-5 Key Links Genomic Location Cytogenetic map 39E2-39E2 Sequence location 2L:21,578,292..21,589,423 [-] Recombination map (full details) 2-54 RefSeq locus NT_033779 REGION: 21578292..21589423 Sequence Get Sequence Get Decorated … WebPrimary cilia are required for several signaling pathways, but their function in cellular morphogenesis is poorly understood. Here we show that emergence of an hexagonal cellular pattern during development of the corneal endothelium (CE), a monolayer of neural crest-derived cells that maintains corneal transparency, depends on a precise temporal … psychologist crystal lake ilWebKevin Gregory-Evans, ...Richard G. Weleber, in Retina (Fifth Edition), 2013 Bardet–Biedl syndrome and the “BBSome” Recently it has been proposed that many of the proteins encoded by Bardet–Biedl genes form complexes, e.g., BBS1, BBS2, BBS4, BBS5,BBS7, BBS8 and BBS9 – the “BBSome.” 520 The complex is important in the function of … host at church say crossword clue

"Web14 jan. 2024 · We found, for example, that most IFT88 protein is lost in Ift88 conditional mutants as expected. However, the cilia persist on adult neurons within the brain in the … " - Ift88 function

Ift88 function

IFT88 Gene - GeneCards IFT88 Protein IFT88 Antibody

WebIFT88 (D13S1056E, hTg737, MGC26259, Tg737, TTC10) protein expression summary. We use cookies to enhance the usability of our website. ... Protein function (UniProt) i. … Web10 mei 2024 · LOF of the IFT88 gene resulted in a marked defect in ciliogenesis and mitochondrial oxidative function. Gene expression patterns in IFT88-deficient thyroid …

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Web1 mei 2024 · Semantic Scholar extracted view of "Ift88 limits bone formation in maxillary process through suppressing apoptosis." ... It is demonstrated that IFT88 has a highly …

Web15 apr. 2024 · IFT88 mediates angiogenesis by regulating the migration, polarization, proliferation, and oriented division of vascular endothelial cells. Further mechanistic … Webepithelial cells, in part via regulating IFT88 expression. It is advised that CBNPs may additionally set off inflammatory responses in bronchial epithelial cells via an HDAC6/IFT88-dependent pathway. ... with unfavourable organic effects and due to the range of functions and viable human exposures to nanoparticles, it is consequently essential

Web20 sep. 2015 · Department of Pediatrics, Mount Sinai School of Medicine, New York, New YorkDepartment of Pediatrics, Case Western Reserve University, Cleveland, OhioDepa ... ,干细胞之家 - 中国干细胞行业门户第一站 WebLike mammalian LICs, D1bLIC has a phosphate-binding domain (P-loop) at its N-terminus. To investigate the function of this conserved domain, d1blic mutant cells were transformed with constructs ... locus affects a component of the ciliary transport (IFT) mechanism, the IFT88 polypeptide. In mutant retina, cilia are generated but not maintained ...

WebAnother component of the IFT system is Ift88, which is essential for the formation of primary cilia. In fact, mutant mice that carry a hypomorphic allele for Ift88 show reduced numbers of cilia and weakened Shh signaling, indicated by decreased up-regulation of Shh targets such as Gli1 and PTCH1.

WebIFT88 30 IFT88 is a component of anterograde IFT and is required for ciliogenesis,4 and thus ORPK mice have abnormally short or missing cilia,27 linking primary cilia and … host atomsWebFujii R, Hasegawa S, Maekawa H, Inoue T, Yoshioka K, Uni R, Ikeda Y, Nangaku M, Inagi R.: Decreased IFT88 expression with primary cilia shortening causes mitochondrial dysfunction in cisplatin-induced tubular injury.. American journal of physiology. Renal physiology : 2024. doi: 10.1152/ajprenal.00673.2024. (IF: 4.097) host at media cityWeb30 aug. 2024 · IFT88 plasmid (pEF5-FRT-TagRFP-IFT88), purchased from Addgene (no. 61684), was transfected into 3′-UTR knockdown cells and enriched with hygromycin (100 … psychologist crown st medical centreWeb(Click on the icon in the table below to see search hit context) psychologist cumberland riWebIntraflagellar transport (IFT) is essential for cilium and flagellar assembly. This movement is accomplished by two IFT complexes: A and B. IFT88, intraflagellar protein 88, is a core … psychologist culver cityhttp://www.cancerindex.org/geneweb/IFT88.htm host attachmentWebNormal mammary development and function in mice with Ift88 deleted in MMTV- and K14-Cre expressing cells Cilia March 4, 2014 Other authors. See publication. WNT5A Inhibits ... psychologist daily activities